Nick Burkhardt (David Giuntoli) is a homicide detective who is given new responsibilities after discovering that he is a descendant of the Grimm, a secret society. His main goal is to find a balance between real life and mythology. The new routine brings challenges and dangers, especially for Nick's fiancée, Juliette Silverton (Bitsie Tulloch), and his coworker, Hank Griffin (Russell Hornsby).